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    Please use this identifier to cite or link to this item: http://asiair.asia.edu.tw/ir/handle/310904400/108692


    Title: Association between chronic obstructive pulmonary disease and increased risk of benign prostatic hyperplasia: a retrospective nationwide cohort study
    Authors: Peng,Yi-Hao;黃建文;Chien-Wen Huang;Lia, Wei-Chih;Liao,Wei-Chih;Che,Hsuan-Ju;Chen, Hsuan-Ju;Ming-Chien Y;Yin,Ming-Chien;Huan, Yu-Ming;Huang,Yu-Ming;吳聰能;Wu,Trong-Neng;Ho,Wen-Chao
    Contributors: 健康產業管理學系
    Date: 2017-05
    Issue Date: 2017-12-22 15:12:53 (UTC+8)
    Abstract: Objective Chronic obstructive pulmonary disease (COPD)
    and benign prostatic hyperplasia (BPH) are common
    disorders in ageing male populations. Nevertheless, the
    relationship between the two diseases has rarely been
    explored. The objective of this study was to examine
    whether patients with COPD are at an increased risk of
    BPH.
    Design Retrospective nationwide cohort study.
    Setting Data retrieved from the Taiwan National Health
    Insurance Research Database.
    Participants Overall, 19 959 male patients aged 40
    years and over with newly diagnosed COPD between 2000
    and 2006 were included as the COPD group, and 19 959
    sex-matched and age-matched enrollees without COPD
    were included as the non-COPD group. Both groups were
    followed-up until the end of 2011.
    Outcome measures A Cox proportional hazards
    regression model was used to compute the risk of BPH
    in patients with COPD compared with enrollees without
    COPD.
    Results The overall incidence rate of BPH was 1.53
    times higher in the COPD group than that in the nonCOPD
    group (44.7 vs 25.7 per 1000 person-years, 95% CI
    1.46 to 1.60) after adjusting for covariates. An additional
    stratified analysis revealed that this increased risk of BPH
    in patients with COPD remained significantly higher than
    that in enrollees without COPD in all men aged 40 years
    and over.
    Conclusion After adjustment for covariates, male patients
    with COPD were found to be at a higher risk of BPH.
    We suggest that clinicians should be cautious about the
    increased risk of BPH in male patients with COPD.
    Relation: BMJ Open
    Appears in Collections:[健康產業管理學系] 期刊論文

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