ASIA unversity:Item 310904400/111479
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    题名: A PEG-based hydrogel for effective wound care management
    作者: Chen, Sen-Lu;Chen, Sen-Lu;傅如輝;Lia, Shih-Fei;Liao, Shih-Fei;劉詩平;Liu, Shih-Ping;Shinn-Zong, L;Lin, Shinn-Zong;Wang, Yu-Chi;Wang, Yu-Chi;*
    贡献者: 社會工作學系
    日期: 2018-02
    上传时间: 2018-10-09 13:29:58 (UTC+8)
    摘要: It is extremely challenging to achieve strong adhesion in soft tissues while minimizing toxicity, tissue damage, and other side effects caused by wound sealing materials. In this study, flexible synthetic hydrogel sealants were prepared based on polyethylene glycol (PEG) materials. PEG is a synthetic material that is nontoxic and inert and, thus, suitable for use in medical products. We evaluated the in vitro biocompatibility tests of the dressings to assess cytotoxicity and irritation, sensitization, pyrogen toxicity, and systemic toxicity following the International Organization for Standardization 10993 standards and the in vivo effects of the hydrogel samples using Coloskin liquid bandages as control samples for potential in wound closure.
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