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    Please use this identifier to cite or link to this item: http://asiair.asia.edu.tw/ir/handle/310904400/111584


    Title: Pteris multifida, Cortex phellodendri, and probiotics attenuated inflammatory status and immunity in mice with a Salmonella enterica serovar Typhimurium infection
    Authors: 殷湄晶;Yin, Mei-chin;Chiung-Hung;Chang, Chiung-Hung;Chiu-Hsian, S;Su, Chiu-Hsian;Yu, Bi;Yu, Bi;Hsu, Yuan-Man;Hsu, Yuan-Man;*
    Contributors: 食品營養與保健生技學系
    Keywords: Cortex phellodendri;Pteris multifidi;Salmonella enterica serovar Typhimurium;cytokines;immunoglobulin;probiotics
    Date: 2018-05
    Issue Date: 2018-10-22 11:36:01 (UTC+8)
    Abstract: Pteris multifida (PM) and Cortex phellodendri (CP) are medicinal foods used for gastrointestinal protection. Lactic-acid bacteria are probiotics. Salmonella Typhimurium strain ST21-infected mice were used to examine the alleviative effects of two lactic-acid bacteria (LAB) as well as aqueous extracts of PM and CP for a 4-day treatment. CP and LAB decreased fecal ST counts. CP and PM reduced the ST21 count in the blood, intestine, and liver. LAB lowered the ST21 count in the intestine and spleen. CP and LAB decreased the IFN-gamma level; PM lowered the TNF-alpha level; and both LAB and PM reduced the IL-1beta level in serum. PM and CP lowered the IgG level in serum. The data in a macrophage infection model indicate that TNF-alpha was partial involved in this alleviative effects, other mechanisms might be involved. In sum, these novel findings suggest that PM, CP, and LAB probiotics are potential anti-Salmonellae agents.
    Relation: BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
    Appears in Collections:[Department of Food Nutrition and Healthy Biotechnology] Journal Article

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