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    Please use this identifier to cite or link to this item: http://asiair.asia.edu.tw/ir/handle/310904400/111998


    Title: Effect of length of time from diagnosis to treatment on colorectal cancer survival: A population-based study
    Authors: 李永恆;YH, Lee;龔佩珍;Kung, Pei-Tseng;王悅馨;YH, Wang;郭娓吟;WY, Kuo;高素琳;SL, Kao;蔡文正;WC, Tsai
    Contributors: 健康產業管理學系
    Date: 2019-01
    Issue Date: 2019-09-10 14:16:05 (UTC+8)
    Abstract: Evidence is limited regarding the effect of diagnosis-to-treatment interval (DTI) on the survival of colorectal cancer (CRC) patients. In addition, previous studies on treatment delay and CRC survival have largely grouped patients from all stages (I-IV) into one cohort. Our study provides analysis on each stage individually. We conducted a retrospective cohort study with 39,000 newly diagnosed CRC patients obtained from the Taiwan Cancer Registry Database from 2004–2010 to examine the effect of DTIs on overall survival. DTIs were divided into 3 groups: ≤ 30 days (36,115 patients, 90.5% of study patients), 31–150 days (2,533, 6.4%), and ≥ 151 days (1,252, 3.15%). Risk of death was increased for DTI 31–150 days (hazard ratio 1.51; 95% confidence interval 1.43–1.59) and DTI ≥ 151 days (1.64; 1.54–1.76) compared to DTI ≤ 30. This risk was consistent across all cancer stages. Additional factors that increased risk of death include male gender, age >75, Charlson Comorbidity Index ≥7, other catastrophic illnesses, lack of multidisciplinary team involvement, and treatment in a low volume center. From these results, we advise that the DTI for all CRC patients, regardless of cancer staging, should be 30 days or less.
    Relation: PLoS One
    Appears in Collections:[健康產業管理學系] 期刊論文

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