English  |  正體中文  |  简体中文  |  Items with full text/Total items : 90453/105671 (86%)
Visitors : 16032033      Online Users : 135
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version


    Please use this identifier to cite or link to this item: http://asiair.asia.edu.tw/ir/handle/310904400/112689


    Title: Association of Caspase-8 Genotypes With Bladder Cancer Risk
    Authors: CHEN, MENG;CHEN, MENG;TS, YUEH-TING;TSAI, YUEH-TING;CHA, WEN-SHIN;CHANG, WEN-SHIN;LIANG-CHUN, S;SHIH, LIANG-CHUN;SHEN, TE-CHUN;SHEN, TE-CHUN;MENG-LIANG, LIANG L;LIN, MENG-LIANG;趙哲毅;Chao, Che-Yi;WANG, YUN-CHI;WANG, YUN-CHI;TSA, CHIA-WEN;TSAI, CHIA-WEN;BAU, DA-TIAN;BAU, DA-TIAN
    Contributors: 食品營養與保健生技學系
    Keywords: Bladder cancer;case–control study;caspase-8;genotype;polymorphism. Copyright© 2019, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.
    Date: 2019-09
    Issue Date: 2020-08-20 13:27:26 (UTC+8)
    Publisher: 亞洲大學
    Abstract: Background/Aim: Rs3824129 is a functional six-nucleotide insertion(I)/deletion(D) polymorphism in the promoter region of caspase 8, an essential apoptosis gene. We aimed to examine the association of this polymorphism with the risk of bladder cancer in the Taiwanese population. Materials and Methods: Caspase-8 rs3834129 genotypes were determined and their associations with bladder cancer risk were evaluated among 375 patients and 375 controls by the PCR-RFLP methodology. In addition, the interaction of caspase-8 rs3834129 genotypes with personal behaviors and clinicopathological features were examined. Results: The frequencies of II, ID and DD genotypes for caspase-8 rs3834129 were non-differentially distributed between the two groups (p for trend=0.7187). Analysis of allelic frequency distribution also indicated that the D variant allele was not associated with a risk of bladder cancer. There was no obvious joint interaction between caspase-8 rs3834129 genotypes and smoking, alcohol consumption, and clinical stage and grade. Conclusion: Caspase-8 rs3834129 genotypes play a minor role in the personal susceptibility to bladder cancer in Taiwan.
    Relation: ANTICANCER RESEARCH
    Appears in Collections:[食品營養與保健生技學系] 期刊論文

    Files in This Item:

    There are no files associated with this item.



    All items in ASIAIR are protected by copyright, with all rights reserved.


    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback