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    ASIA unversity > 醫學暨健康學院 > 心理學系 > 期刊論文 >  Item 310904400/15864


    Please use this identifier to cite or link to this item: http://asiair.asia.edu.tw/ir/handle/310904400/15864


    Title: Neuropsychological Functions in Patients with Bipolar I and Bipolar II Disorder
    Authors: Yih-Lynn Hsiao;Yi-Syuan Wu;Jo Yung-Wei Wu;Min-Hsien Hsu;Hui-Chun Chen;Sheng-Yu Lee;I-Hui Lee;Tzung-Lieh Yeh;Yen-Kuang Yang;Huei-Chen Ko;Ru-Band Lu
    Contributors: 心理學系
    Date: 2009-08
    Issue Date: 2012-11-23 15:03:29 (UTC+8)
    Abstract: The literature reports persistent cognitive impairments in patients with bipolar disorder even after prolonged remission. However, a majority of studies have focused only on bipolar I disorder (BP-I), primarily because bipolar II disorder (BP-II) is often underdiagnosed or misdiagnosed. More attention should be paid to the differences between BP-I and BP-II, especially the aspects of neuropsychological functioning. We examined the different neuropsychological functions in BP-I and BP-II patients and compared them with those of healthy controls. Methods: The study included 67 patients with interepisode bipolar disorder (BP-I: n = 30; BP-II: n = 37) and 22 healthy controls compared using a battery of neuropsychological tests that assessed memory, psychomotor speed, and certain aspects of frontal executive function. Results: The BP-I group performed poorly on verbal memory, psychomotor speed, and executive function compared to the BP-II and control groups. Both bipolar groups performed significantly less well than the control group on measures of working memory and psychomotor speed, while the BP-II group showed an intermediate level of performance in psychomotor speed compared to the BP-I and control groups. There was no difference between the groups on visual memory. Conclusions: BP-I was characterized by reduced performance in verbal memory, working memory, psychomotor speed, and executive function, while BP-II patients showed a reduction only in working memory and psychomotor speed. Cognitive impairment existed in both subtypes of bipolar disorder, and was greater in BP-I patients. Rehabilitation interventions should take into account potential cognitive differences between these bipolar subtypes.
    Relation: BIPOLAR DISORDERS, 11(5):547-54
    Appears in Collections:[心理學系] 期刊論文

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