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    Please use this identifier to cite or link to this item: http://asiair.asia.edu.tw/ir/handle/310904400/16294


    Title: Octreotide Therapy in Asparaginase-Associated Pancreatitis in Childhood Acute Lymphoblastic Leukemia
    Authors: 彭慶添
    Contributors: 生物科技學系
    Date: 2008-12
    Issue Date: 2012-11-23 17:11:05 (UTC+8)
    Abstract: Little is known about octreotide therapy in asparaginase-associated pancreatitis (AAP) in children. Of the 59 children with acute lymphoblastic leukemia (ALL) receiving E. coli L-asparaginase, 5 patients (8.5%) developed AAP. Octreotide was administered to four patients. Clinical and laboratory improvement were evident after octreotide therapy. There were no deaths and no severe adverse side effects were noted. No pseudocysts were detected; however, two of the four patients developed diabetes. One child without octreotide treatment developed chronic pancreatitis and pseudocyst. We conclude that octreotide therapy appears to be safe and potentially beneficial in the management of AAP in children.
    Relation: PEDIATRIC BLOOD & CANCER;51(6):824-5.
    Appears in Collections:[生物科技學系] 期刊論文

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