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    Please use this identifier to cite or link to this item: http://asiair.asia.edu.tw/ir/handle/310904400/16813


    Title: A circuit design of a low-cost, portable and programmable electroporation device for biomedical applications
    Authors: 程德勝;Ching, Congo Tak-Shing;黃素華;Huang, Su-Hua;蕭進松;Hsiao, Chin-Sung;張剛鳴;Chang, Kang-Ming
    Contributors: 生物科技學系
    Keywords: Electroporation;Low-cost;Programmable;Biomedical
    Date: 2012-03
    Issue Date: 2012-11-23 17:17:18 (UTC+8)
    Abstract: Electroporation for transdermal drug delivery or for non-invasive monitoring of patients could allow a new generation of medical devices to be developed for low-cost healthcare. The existing electroporation systems today are bulky, expensive or not fully programmable. Therefore, a compact, low-cost and programmable device was developed and evaluated. A circuit is described herein which provides a variety of adjustable high-voltage (2–300 V) electric waveforms (pulsed and pulsed-biphasic) for electroporation. Evaluation showed that this device provides for precise regulation of the magnitude and waveform of a high-voltage over a wide range of impedance, important for in vivo/human use. Also, the device was evaluated in vitro to be capable of enhancing transdermal extraction of metabolites, like uric acid, for non-invasive monitoring and transdermal delivery of medications, like insulin, for non-invasive drug delivery.
    Relation: SENSORS AND ACTUATORS B-CHEMICAL
    Appears in Collections:[生物科技學系] 期刊論文

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