English  |  正體中文  |  简体中文  |  Items with full text/Total items : 90451/105768 (86%)
Visitors : 11067926      Online Users : 647
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version


    Please use this identifier to cite or link to this item: http://asiair.asia.edu.tw/ir/handle/310904400/17311


    Title: Xylooligosaccharides and fructooligosaccharides affect the intestinal microbiota and precancerous colonic lesion development in rats
    Authors: Cheng-Kuang Hsu;Jiunn-Wang Liao;Yun-Chin Chung;Chia-Pei Hsieh;Yin-Ching Chan
    Contributors: 保健營養生技學系
    Keywords: prebiotic;xylooligosaccharides;fructooligosaccharides;bifidobacteria aberrant crypt foci
    Date: 2004-06
    Issue Date: 2012-11-26 10:31:21 (UTC+8)
    Abstract: Certain nondigestible oligosaccharides can be selectively utilized by probiotics and reduce the risk
    of colon cancer. However, the inhibitory effects of xylooligosaccharides (XOS) on colon cancer are not well
    documented. This study evaluated the effects of xylooligosaccharides and fructooligosaccharides (FOS) on the
    alteration of cecal microbiota, cecal pH, cecal weight, and serum lipid levels, and also their inhibitory effect on
    precancerous colon lesions in male Sprague-Dawley rats. The rats were randomly assigned to 4 groups: control,
    treatment with 1,2-dimethylhydrazine (DMH) [15 mg/(kg body wt wk) for 2 wk], treatment with DMH 60 g
    XOS/kg diet, and treatment with DMH 60 g FOS/kg diet. Rats were fed the experimental diets for 35 d, beginning
    1wk after the second dose of DMH. Both XOS and FOS markedly decreased the cecal pH and serum triglyceride
    concentration, and increased the total cecal weight and bifidobacteria population. XOS had a greater effect on the
    bacterial population than did FOS. Moreover, both XOS and FOS markedly reduced the number of aberrant crypt
    foci in the colon of DMH-treated rats. These results suggest that XOS and FOS dietary supplementation may be
    beneficial to gastrointestinal health, and indicate that XOS is more effective than FOS.
    Relation: JOURNAL OF NUTRITION, 134(6):1523-1528.
    Appears in Collections:[食品營養與保健生技學系] 期刊論文

    Files in This Item:

    File Description SizeFormat
    index.html0KbHTML136View/Open


    All items in ASIAIR are protected by copyright, with all rights reserved.


    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback