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    Please use this identifier to cite or link to this item: http://asiair.asia.edu.tw/ir/handle/310904400/17808


    Title: Metabolic syndrome is associated with change in arterial stiffness - A community-based Taichung Community Health Study
    Authors: Chia-Ing Li;Sharon LR Kardia;Chiu-Shong Liu;Wen-Yuan Lin;Chih-Hsueh Lin;Yi-Dar Lee;Fung-Chang Sung;Tsai-Chung Li;Cheng-Chieh Lin
    Contributors: 健康產業管理學系
    Keywords: metabolic syndrome;pulse wave velocity;arterial stiffness
    Date: 2011
    Issue Date: 2012-11-26 12:03:54 (UTC+8)
    Abstract: Background
    The aim of this study was to evaluate the effect of MetS on arterial stiffness in a longitudinal study.
    Methods
    Brachial-ankle pulse wave velocity (baPWV), a measurement interpreted as arterial stiffness, was measured in 1518 community-dwelling persons at baseline and re-examined within a mean follow-up period of 3 years. Multivariate linear regression with generalized estimating equations (GEE) were used to examine the longitudinal relationship between MetS and its individual components and baPWV, while multivariate logistic regression with GEE was used to examine the longitudinal relationship between MetS and its individual components and the high risk group with arterial stiffness.
    Results
    Subjects with MetS showed significantly greater baPWV at the end point than those without MetS, after adjusting for age, gender, education, hypertension medication and mean arterial pressure (MAP). MetS was associated with the top quartile of baPWV (the high-risk group of arterial stiffness, adjusted odds ratio [95% confidence interval] 1.52 [1.21-1.90]), and a significant linear trend of risk for the number of components of MetS was found (p for trend < 0.05). In further considering the individual MetS component, elevated blood pressure and fasting glucose significantly predicted a high risk of arterial stiffness (adjusted OR [95% CI] 3.72 [2.81-4.93] and 1.35 [1.08-1.68], respectively).
    Conclusions
    MetS affects the subject's progression to arterial stiffness. Arterial stiffness increased as the number of MetS components increased. Management of MetS is important for preventing the progression to advanced arterial stiffness.
    Relation: BMC PUBLIC HEALTH, 11(1):808-815.
    Appears in Collections:[健康產業管理學系] 期刊論文

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