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    Title: Assessment of corneal biomechanical properties and intraocular pressure with Ocular Response Analyzer in childhood myopia.
    Authors: Pei-Yao Chang;Shu-Wen Chang;Jiun-Yi Wang
    Contributors: 健康產業管理學系
    Date: 2010-10
    Issue Date: 2012-11-26 12:06:55 (UTC+8)
    Abstract: "Background/aims The authors estimated the
    association between corneal biomechanical properties
    and axial length in myopic children and verified the
    relationship between axial length and intraocular
    pressure (IOP).
    Methods This cross-sectional study included 126 eyes
    of 63 children, aged 12.0263.19 years. Corneal
    hysteresis (CH), corneal resistance factor (CRF), central
    corneal thickness (CCT) and IOP were recorded with the
    Reichert Ocular Response Analyzer. Axial length (AL) and
    anterior chamber depth (ACD) were measured by the
    IOLMaster, whereas corneal curvature was measured by
    an autorefractor.
    Results In multivariable mixed model analysis, CH
    correlated significantly with AL (p<0.0001), ACD
    (p¼0.044) and CCT (p<0.0001), but not with curvature;
    CRF correlated significantly with AL (p¼0.004) and CCT
    (p<0.0001) but not ACD or curvature. The difference in
    CH between the two eyes of each patient correlated
    significantly with the difference in the AL between the
    two eyes (p¼0.002). IOP did not correlate with age,
    gender or AL.
    Conclusion Lower CH and CRF were associated with
    longer AL but not corneal curvature. The association
    between lower CH and deeper ACD demonstrated the
    importance of CH as a determinant of ocular biometry in
    both the anterior and posterior segments. Differences in
    corneal biomechanical properties may indicate more
    generalised structural differences between eyes."
    Appears in Collections:[Department of Healthcare Administration] Journal Article

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