ASIA unversity:Item 310904400/25217
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 90570/105786 (86%)
造訪人次 : 16338967      線上人數 : 310
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧:
  • 您可在西文檢索詞彙前後加上"雙引號",以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋,建議至進階搜尋限定作者欄位,可獲得較完整資料
  • 進階搜尋


    題名: Thymoquinone induces apoptosis in oral cancer cells through P38β inhibition
    作者: Abdelfa, Ehab;Abdelfadil, Ehab;Chen, Ya-Hsin;Cheng, Ya-Hsin;Bau, Da-Tian;Bau, Da-Tian;Ting, Wei-Jen;Ting, Wei-Jen;Chen, Li-Mien;Chen, Li-Mien;Hs, Hsi-Hsien;Hsu, Hsi-Hsien;Lin, Yueh-Min;Lin, Yueh-Min;Che, Ray-Jade;Chen, Ray-Jade;黃志揚;HUANG, CHIH-YANG
    貢獻者: 生物科技學系
    日期: 2013
    上傳時間: 2013-07-11 13:55:49 (UTC+8)
    摘要: Oral cancer is a common malignancy associated with high morbidity and mortality. While p38 MAPK is reported to be involved in different cellular activities such as proliferation and differentiation, reports rarely define the roles of the individual members of the p38 MAPK family in cancer. We used two unique cell lines developed by our lab representing chemically induced oral cancer cells (T28) and non-tumor cells (N28) obtained from tissues surrounding the induced cancer as a model to screen out whether p38 MAPK is involved in the malignant transformation processes. The results suggest an association between p38β not p38α and oral cancer development. Additionally, the anti-cancer activity of thymoquinone (TQ) was screened out and we found evidences suggesting that the anti-tumor activity of TQ may be attributed to the downregulation of p38β MAPK.
    顯示於類別:[生物科技學系] 期刊論文




    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋