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    Please use this identifier to cite or link to this item: http://asiair.asia.edu.tw/ir/handle/310904400/25275

    Title: Antioxidant and anti-inflammatory properties of taiwanese yam (Dioscorea japonica Thunb. var. pseudojaponica (Hayata) Yamam.)and its reference compounds.
    Authors: Chuan-Sung, C;Chiu, Chuan-Sung;鄧正賢;Deng, Jeng-Shyan;Ch, Heng-Yuan;Chang, Heng-Yuan;Che, Yi-Chuan;Chen, Yi-Chuan;李明明;Lee, Min-Min;Hou, Wen-Chi;Hou, Wen-Chi;Le, Chao-Ying;Lee, Chao-Ying;Shyh-Shyun, H;Huang, Shyh-Shyun;Guan-Jhong, H;Huang, Guan-Jhong
    Contributors: 保健營養生技學系
    Keywords: Taiwanese yam;Dioscorea japonica Thunb. var. pseudojaponica;Antioxidant;Anti-inflammation
    Date: 2013-05
    Issue Date: 2013-07-11 14:02:06 (UTC+8)
    Abstract: Dioscorea japonica Thunb. var. pseudojaponica (DP) is consumed as food and widely used in traditional Chinese medicine in Taiwan. The aims of this study are to investigate the antioxidant and anti-inflammatory effects of ethanol extract of DP (EDP) and its reference compounds. Fingerprint chromatogram from HPLC indicated that EDP contains gallic acid and vanillic acid. EDP was evaluated for its antioxidant effects and LPS-induced nitrite oxide (NO) production in RAW264.7 cells. EDP decreased the LPS-induced NO production and expressions of iNOS and COX-2 in RAW264.7 cells. In-vivo anti-inflammatory activities of EDP were assessed in mouse paw oedema induced by λ-carrageenan (Carr). We investigated the antioxidant mechanism of EDP via studies of the activities of catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase (GPx) and the levels of malondialdehyde (MDA) in the oedematous paw. The results showed that EDP might be a natural antioxidant and anti-inflammatory agent
    Relation: FOOD CHEMISTRY, 141(2):1087–1096.
    Appears in Collections:[食品營養與保健生技學系] 期刊論文

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