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    ASIA unversity > 醫學暨健康學院 > 期刊論文 >  Item 310904400/6778


    Please use this identifier to cite or link to this item: http://asiair.asia.edu.tw/ir/handle/310904400/6778


    Title: More activated cardiac mitochondrial dependent apoptotic pathway in obese Zucker rat
    Authors: Lu MC;Tzang BS;Wu FL;Yueh-Sheng Chen;Chang-Hai Tsai;黃志揚;Shin-Da Lee
    Date: 2007-11
    Issue Date: 2009-12-23 14:22:16 (UTC+8)
    Publisher: Asia University
    Abstract: Background: Obesity is often associated with the development of heart failure, but the precise mechanisms remain uncertain. The purpose of this study was to evaluate the key components of the mitochondrial-dependent apoptotic pathway in excised heart from obese Zucker rats.
    Methods: Twelve obese Zucker rats were studied at 5 to 6 months of age, and 12 age-matched lean Zucker rats served as control. The myocardial architecture and key components of the mitochondrial-dependent apoptotic pathway in the excised left ventricle from rats were measured by histopathological analysis, Western blotting, and reverse transcription polymerase chain reaction (RT-PCR).
    Relation: OBESITY RESEARCH 11 (15): 2634-2642
    Appears in Collections:[醫學暨健康學院] 期刊論文

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