ASIA unversity:Item 310904400/79772
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    题名: Predisposing Risk Factors for Delirium in Living Donor Liver Transplantation Patients in Intensive Care Units
    作者: Wang, SH;Wang, SH;王俊毅;Wang, Jiun-Yi;Lin, PY;Lin, PY;Lin, KH;Lin, KH;Ko, CJ;Ko, CJ;Hsieh, CN;Hsieh, CN;Lin, HC;Lin, HC;Chen, YL;Chen, YL
    贡献者: 健康產業管理學系
    日期: 2014-05
    上传时间: 2014-06-05 12:06:25 (UTC+8)
    摘要: Background

    Delirium is one of the main causes of increased length of intensive care unit (ICU) stay among patients who have undergone living donor liver transplantation (LDLT). We aimed to evaluate risk factors for delirium after LDLT as well as to investigate whether delirium impacts the length of ICU and hospital stay.

    Methods

    Seventy-eight patients who underwent LDLT during the period January 2010 to December 2012 at a single medical center were enrolled. The Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) scale was used to diagnose delirium. Preoperative, postoperative, and hematologic factors were included as potential risk factors for developing delirium.

    Results

    During the study period, delirium was diagnosed in 37 (47.4%) patients after LDLT. The mean onset of symptoms occurred 7.0±5.5 days after surgery and the mean duration of symptoms was 5.0±2.6 days. The length of stay in the ICU for patients with delirium (39.8±28.1 days) was significantly longer than that for patients without delirium (29.3±19.0 days) (p<0.05). Risk factors associated with delirium included history of alcohol abuse [odds ratio (OR) = 6.40, 95% confidence interval (CI): 1.85–22.06], preoperative hepatic encephalopathy (OR = 4.45, 95% CI: 1.36–14.51), APACHE II score ≥16 (OR = 1.73, 95% CI: 1.71–2.56), and duration of endotracheal intubation ≥5 days (OR = 1.81, 95% CI: 1.52–2.23).

    Conclusions

    History of alcohol abuse, preoperative hepatic encephalopathy, APACHE II scores ≥16 and endotracheal intubation ≥5 days were predictive of developing delirium in the ICU following liver transplantation surgery and were associated with increased length of ICU and hospital stay.
    關聯: PLoS One,9(5):e96676.
    显示于类别:[國際企業學系] 期刊論文

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