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    Please use this identifier to cite or link to this item: http://asiair.asia.edu.tw/ir/handle/310904400/79846

    Title: Investigation of Anti-Infection Mechanism of Lactoferricin and Splunc-1
    Authors: Yung An Tsou;Hung-Jin Huang;Wesley Wen Yang Lin;Calvin Yu-Chian Chen
    Contributors: 生物科技學系
    Date: 2014-04
    Issue Date: 2014-06-05 12:18:22 (UTC+8)
    Abstract: The innate immune system is the first line in the defense system and prevents the body from further bacteria, virus, or fungal infections. Most of the innate immune system is relevant to mucosa immunity. Lactotransferrin is secreted from the human mammal breast duct epithelial tissue and strengthens infant immunity to defense with regard to outward pathogens. Splunc-1 is also an innate material secreted from the soft palate, lung, nasal cavity epithelium, and mucosa. It helps with mucosa defense against bacterial, virus, and even fungus. LPS is the main etiology of Gram-negative bacilla infection source. And studies of lactoferricin and slpunc-1 both can combine with LPS and subsequently cause insults to the mucosa. Although, we know that both of them partake in an important role in innate immunity, we do not know the effects when they work together. In this study, we just overview silicon stimulation to examine the combination of Lactoferricin and Splunc-1 and the effect with regard to LPS.
    Relation: Evidence-based Complementary and Alternative Medicine
    Appears in Collections:[生物資訊與醫學工程學系 ] 期刊論文

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