English  |  正體中文  |  简体中文  |  Items with full text/Total items : 90452/105769 (86%)
Visitors : 11989002      Online Users : 849
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version

    Please use this identifier to cite or link to this item: http://asiair.asia.edu.tw/ir/handle/310904400/8464

    Title: Transplantation of Endothelial Progenitor Cells as Therapeutics for Cardiovascular Diseases
    Authors: Hung, HS (Hung, Huey-Shan);Shyu, WC (Shyu, Woei-Cherng);Tsai, CH (Tsai, Chang-Hai);Hsu, SH (Hsu, Shan-hui);Lin, SZ (Lin, Shinn-Zong)
    Contributors: Department of Healthcare Administration
    Keywords: Endothelial progenitor cells (EPCs);Cardiovascular diseases;Angiogenesis;Cell therapy
    Date: 2009
    Issue Date: 2010-03-26 10:52:32 (UTC+8)
    Publisher: Asia University
    Abstract: With better understanding of endothelial progenitor cells (EPCs), many therapeutic approaches to cardiovascular diseases have been developed. This article will review novel research of EPCs in promoting angiogenesis, vasculogenesis, and endothelialization, as a design for future clinical treatment. Cell therapy has the potential to supply stem/progenitor cells and multiple angiogenic factors to the region of ischemia. The efficacy of EPC transplantation may be impaired by low survival rate, insufficient cell number, and impaired function in aging and diseases. Combination of EPCs or cells primed with growth factors or genetic modification may improve the therapeutic efficacy. The molecular mechanism involved in EPC repairing processes is essential. Thus, we have also addressed the molecular mechanism of mobilization, homing, and differentiation of EPCs. The potential of therapeutic neovascularization, angiogenic factor therapy, and cell transplantation have been elucidated. Based on past experience and actual knowledge, future strategies for EPC therapy will be proposed in order to fully exploit the potential of EPC transplantation with clinical relevance for cardiovascular disease applications.
    Relation: CELL TRANSPLANTATION 18 (9): 1003-1012
    Appears in Collections:[健康產業管理學系] 期刊論文

    Files in This Item:

    File Description SizeFormat
    98.doc47KbMicrosoft Word487View/Open

    All items in ASIAIR are protected by copyright, with all rights reserved.

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback