ASIA unversity:Item 310904400/91984
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 90452/105769 (86%)
造访人次 : 11946605      在线人数 : 393
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧:
  • 您可在西文检索词汇前后加上"双引号",以获取较精准的检索结果
  • 若欲以作者姓名搜寻,建议至进阶搜寻限定作者字段,可获得较完整数据
  • 进阶搜寻
    ASIA unversity > 醫學暨健康學院 > 期刊論文 >  Item 310904400/91984


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://asiair.asia.edu.tw/ir/handle/310904400/91984


    题名: Improvement of glycemic control in streptozotocin-induced diabetic rats by atlantic salmon skin gelatin hydrolysate as the dipeptidyl-peptidase IV inhibitor
    作者: 謝承紘;Hsieh, Cheng-Hong;王子源;Wang, Tzu-Yuan;洪娟娟;Hung, Chuan-Chuan;陳孟君;Chen, Meng-Chun;徐國強;Hsu, Kuo-Chiang
    贡献者: 圖書館
    日期: 2015-06
    上传时间: 2015-10-08 14:27:29 (UTC+8)
    摘要: In our previous study, Atlantic salmon skin gelatin hydrolysed with flavourzyme possessed 42.5% DPP-IV inhibitory activity at the concentration of 5 mg/mL. The oral administration of hydrolysate (FSGH) at single dose of 300 mg/d in streptozotocin (STZ)-induced diabetic rats for 5 weeks was evaluated for its antidiabetic effect. During the 5-week experiment, body weight was increased, food and water intake were reduced by FSGH in diabetic rats. The daily administration of FSGH for 5 weeks was effective to lower the blood glucose levels of diabetic rats during oral glucose tolerance test (OGTT). After 5-week treatment, plasma dipeptidyl peptidase (DPP)-IV activity was inhibited; plasma active glucagon-like peptide-1 (GLP-1), insulin and insulin-to-glucagon ratio were increased by FSGH in diabetic rats. The results indicate that FSGH has the function of inhibiting GLP-1 degradation by DPP-IV, resulting in the enhancement of insulin secretion and improvement of glycemic control in STZ-induced diabetic rats.
    關聯: Food & Function
    显示于类别:[醫學暨健康學院] 期刊論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    index.html0KbHTML231检视/开启


    在ASIAIR中所有的数据项都受到原著作权保护.


    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈